Snct those systems should have a room of there own.
I cant give you any adive on the laptop or the imac but with the shuttle you can install eather a hotswap drive and take your hd with you to keep her from accessing it or you can install a key lock for the power supply as far as better security than password protecting the cmos i would just pull my harddrives and store them for safe keeping or move them systems to another room under lock and key plus an attack dog.
Or you can do what i do.
Just tell everyone this.
See these systems?
I hold a greater value on there wellness than your life!
If you touch them!
No one will ever find your body!
Get the hint?
That usely scares anyone wanting to touch your systems to second think.