Slackware and Debian are only for hardcore Linux users or servers. I use Slackware on one of my boxes and, next to OpenBSD's installer, I think it is probably the simpest to use.
Wha?!? I didn't become a hardcore Linux user until I had Debian on my box!! Mandy and I did not get along well at all.

All one with no Linux experience needs to get any distro up and running is knowledge of their main components, time, patience, manuals and good help(if possible). When I first tried a Debian install I was not very experienced and it didn't work out. The next time .... same thing. The third time...same thing...but this time I read up more and got somereally good advice and voila Debain installed with out trouble.